Synthesis of Novel Cryptates Based on Triazole Motif: A Regioselective Approach

Abstract

Regioselective syntheses of cryptands were achieved via two different approaches, first by protection–deprotection and second by cyclization reactions between 1,ω-dihaloalkanes and the lariat amino triazolophanes. The syntheses of all triazolophanes and cryptands were carried out regioselectively, and the compounds were obtained in good yields. All compounds were studied and confirmed with different spectroscopic tools.

Keywords:

• Cryptands
• lariat triazolophanes
• macrocycles
• protection–deprotection

ACKNOWLEDGMENTS

The authors acknowledge the scholarships received from the University of Mumbai and government of Maharashtra, and the spectral data obtained from TIFR-Mumbai and instrumentation division, Institute of Science, Mumbai, India.

Notes

Dedicated to Professor R. H. Sahasrabudhe.