Synthesis and Catalytic Applications of Sulfonic Acid Group–Functionalized Nano- and Microsilica Structures

Abstract

Sulfonic acid group–functionalized nano- and microsilica with different sizes and shapes were synthesized. Silica nanospheres with an average size of 225 nm, silica microtubes, and fine silica gel were prepared and functionalized by sulfonic acid. Their catalytic activity was investigated in the three-component Biginelli reaction for the synthesis of dihydropyrimidinones.

Keywords:

• Biginelli reaction
• silica microtubes
• silica nanospheres
• silica sulfuric acid
• supported catalyst

ACKNOWLEDGMENT

Financial support from the Research Council of Shahid Beheshti University and the Catalyst Center of Excellence (CCE) is gratefully acknowledged.

Notes

^a Silica microtubes.

^b Silica nanospheres.

^c Fine silica gel.

^a Silica microtubes.

^b Silica nanospheres.

^c Fine silica gel.