The Efficient Palladium-Catalyzed Selective t Synthesis of Benzenesulfonic Acids

Abstract

Palladium-catalyzed synthetic methodology has been developed for the synthesis of 2-aminobenzenesulfonic acids from benzothiazoles in good to excellent yields using chloramine-B in alkaline (pH 12) acetonitrile/water (1:1) at 80 °C.

Keywords:

• 2-Aminobenzenesulfonic acids
• benzothiazoles
• chloramine-B
• palladium catalyst

Notes

^a Substrate: 1 mmol, Chloramine-B = 5 mmol, temperature = 80 °C, time = 24–26 h.

^b Mps given in parentheses refer to authentic samples.