Abstract
An efficient, safe, and viable process has been developed for large-scale preparation of salidroside, a natural product. The process consists of two chemical steps, which produce the salidroside on a multikilogram scale with 72% overall yield and >98% purity. A series of novel salidroside analogs were prepared according to the same method.
ACKNOWLEDGMENT
This work was financially supported by the National Natural Science Foundation of China (Nos. 20972189, 30901883, and 20802091).