Abstract
Amberlyst-15 can effectively catalyze Cbz protection of aliphatic and aromatic amines within 10–15 min under solvent-free conditions. The catalyst can be used repeatedly without loss of activity, and the reaction requires no workup and gives excellent yields.
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ACKNOWLEDGMENTS
G.B. is grateful to the Council of Scientific and Industrial Research, New Delhi [Scheme No. 0 1 (1992)/05/EMR-II], and the Department of Science and Technology, New Delhi (Scheme No. SR/S1/OC-25/2007), for providing the financial assistance for this work.
Notes
aAll the reactions were conducted at room temperature.
bYield of the purified products.