Cu/SiO₂-Catalyzed One-Pot Synthesis of 12-Aryl-8,9,10,12-tetrahydrobenzo[α]xanthen-11-ones Under Solvent-Free Conditions

Abstract

An efficient and straightforward procedure for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[α]xanthen-11-ones has been achieved by three-component cyclocondensation of aldehyde, β-naphthol, and dimedone under solvent-free conditions.

Graphical Abstract

Keywords:

• Aldehyde
• dimedone
• β-naphthol
• one-pot reaction
• solvent-free

ACKNOWLEDGMENT

We are grateful to Alzahra University Research Council for partial support of this work.

Notes

^aThe amount of 0.05 g of catalyst was used.

^bYields were based on GC analysis.

^aAll the products were characterized by GC, mass, IR, and melting points with those reported in the literature.

^bYield refers to the pure isolated products.