KAl(SO₄)₂ · 12H₂O as a Recyclable Lewis Acid Catalyst for Synthesis of Spirooxindoles in Aqueous Media

Abstract

A simple and efficient procedure for the synthesis of spirooxindole has been described that employs a three-component condensation reaction in one pot using isatin, active methylene reagent, and 1,3-dicarbonyl compounds in an aqueous medium.

Keywords:

• Alum
• spirooxindole
• water

ACKNOWLEDGMENTS

We are grateful to Alzahra University Research Council for partial support of this work.

Notes

^a Isolated yields.

^a Isolated yields.

^a Isolated yields.