Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 42, 2012 - Issue 5
Submit an article Journal homepage
848
Views
13
CrossRef citations to date
0
Altmetric
Original Articles

Application of [3 + 2]-Cycloaddition in the Synthesis of Valdecoxib

Anumula Raghupathi Reddy Research and Development, Dr. Reddy's Laboratories Ltd., Qutubullapur, India; Institute of Science and Technology, J. N. T. University, Hyderabad, India
,
Gilla Goverdhan Research and Development, Dr. Reddy's Laboratories Ltd., Qutubullapur, India
,
Aalla Sampath Research and Development, Dr. Reddy's Laboratories Ltd., Qutubullapur, India
,
Khagga Mukkanti Institute of Science and Technology, J. N. T. University, Hyderabad, India
,
Padi Pratap Reddy Research and Development, Dr. Reddy's Laboratories Ltd., Qutubullapur, IndiaCorrespondence[email protected]
&
Rakeshwar Bandichhor Research and Development, Dr. Reddy's Laboratories Ltd., Qutubullapur, IndiaCorrespondence[email protected]
Pages 639-649 | Received 16 May 2010, Published online: 01 Nov 2011
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in situ–generated nitrile oxide derivatives.

GRAPHICAL ABSTRACT

ACKNOWLEDGMENTS

The authors thank the management of Dr. Reddy's Laboratories Ltd. for supporting this work. Cooperation from colleagues in the Research and Development Department and Analytical Research and Development Department is also acknowledged.

Notes

Dr. Reddy's Communication No. IPM-00206.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.