Abstract
Hydroxytyrosol is a naturally occurred orthodiphenolic component of olive oil. A variety of biological functions for this molecule have been reported. We report herein an efficient and practical method for the chemical synthesis of hydroxytyrosol from 2,3-dihydroxybenzaldehyde.
GRAPHICAL ABSTRACT
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ACKNOWLEDGMENTS
The financial support from Soochow University and the National Science and Technology Major Project on Key Drug Creation and Manufacturing Program (2009ZX09103-129) is gratefully acknowledged. We thank Professor Zhongwu Guo at Wayne State University and Professor Zhengqiang Wang at University of Minnisota for critical revisions.