Novel Synthesis of Bis-Iminocoumarins

Abstract

Reaction of 3-aryl iminocoumarins with diacid chlorides as C-electrophilic reagents under mild conditions novel bis-iminocoumarins in good yields. When the reaction was performed with alkylene dibromides by heating them in toluene in the presence of IRA 900 resin, bis-ether compounds were obtained by way opening the pyranic ring. The structures of the product obtained were characterized by Fourier transform infrared, ¹H NMR, ¹³C NMR, and elemental analysis.

GRAPHICAL ABSTRACT

Keywords:

• Bis-iminocoumarins
• diacid chlorides
• iminocoumarins
• Knoevenagel condensation

ACKNOWLEDGMENT

The authors acknowledge the Ministry of Higher Education, Scientific Research, and Technology in Tunisia for financial support.