Abstract
A highly efficient metal-free catalytic system, 1,3-dibromo-5,5-dimethylhydantoin (DBDMH)–tert-butylnitrite (TBN)–H2O, has been developed for an environmentally friendly and economical aerobic acid-free oxidation of sulfides. TBN was identified as an efficient NO equivalent for the activation of molecular oxygen. Under optimal conditions, a variety of sulfides substrates were converted into their corresponding sulfoxides in good yields by molecular oxygen.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
The research was supported by Program for Changjiang Scholars and Innovative Research Team in University (IRT0711).
Notes
a Reaction conditions: methyl phenyl sulfide (10 mmol), DBDMH 0.0572g (2 mol%), TBN 0.05 mL (4 mol%), CH3CN (20 mL), O2 (0.8 MPa), 50 °C (oil bath temperature), 2 h.
b Conversions were determined by GC with area normalization.
c Isolated yield.
a Reaction conditions: substrates (10 mmol), DBDMH 0.0572 g (2 mol%), TBN 0.05 mL (4 mol%), CH3CN (20 mL), H2O (1.5 mL), 50 °C (oil bath temperature).
b Conversions were determined by GC with area normalization.
c Isolated yield.