Synthesis of Di(6-aminouracil-5-yl)-arylmethane: A New Product of the Reaction of 6-Aminouracil with Aldehyde

Abstract

In this article, a new result of the reaction of 6-aminouracil with aldehyde catalyzed by BF₃ and aniline is established, which gives a new strategy for the synthesis of di(6-aminouracil-5-yl)-arylmethane. The simple and convenient synthetic procedure and formation of di(6-aminouracil-5-yl)-arylmethane render this method very useful in synthetic and medicimal chemistry.

GRAPHICAL ABSTRACT

Keywords:

• 6-Aminouracil
• cocatalyst
• di(6-aminouracil-5-yl)-arylmethane
• synthesis

ACKNOWLEDGMENTS

This research was supported by the Cultivation and Construction Fund for the State Key Subject of Physical Chemistry. We thank the Testing Center of Yangzhou University for characterizing our compounds.