Abstract
An efficient and environmentally benign process for the synthesis of quinoxalines has been developed using glycerine–cerium chloride as a reaction medium. This method is applicable to a variety of diketones and 1,2-phenylenediamines to afford the corresponding quinoxaline derivatives in excellent yields. The reaction medium was recovered and reused for further reactions without any problem.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
J. K. K. is thankful to the University Grants Commission, New Delhi, for providing a fellowship.
Notes
a All the products were identified by their 1H NMR, IR, and mass.
b Yields were isolated and not optimized.