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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 42, 2012 - Issue 6
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Original Articles

Convenient One-Step Synthesis of cis-2,4,5-Triarylimidazolines from Aromatic Aldehydes with Urea

, &
Pages 905-913 | Received 11 Mar 2010, Published online: 11 Nov 2011
 

Abstract

A simple and efficient method has been developed for the synthesis of cis-2,4,5-triarylimidazolines based on a one-step procedure of aldehydes and urea in the presence of cesium carbonate.

GRAPHICAL ABSTRACT

ACKNOWLEDGMENT

This work was supported by the National Natural Science Foundation of China (20972085 and 21032004).

Notes

a The reactions were performed with 1.0 mmol aldehyde 1a, 4.0 mmol urea, and 2.0 mmol base in 2 mL solvent.

b Determined by 1H NMR using CH2Cl2 as internal standard.

a NMR yields, isolated yields are given in parentheses.

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