Abstract
A mild, efficient, and solvent-free microwave (MW)–promoted Biginelli reaction for the synthesis of 3,4-dihydropyrimidin-2(1H)-(thio)ones in nitrite ionic liquid (IL-ONO) is described. This ionic liquid is a weak Lewis base catalyst, which can be easily recovered and reused in several runs. The satisfactory results were obtained with good yields and short reaction time, using a simple experimental procedure.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENTS
The partial financial assistance from the research vice chancellor of Islamic Azad University of Mianeh and Azerbaijan University of Tarbiat Moallem is gratefully acknowledged.
Notes
a Isolated yields of products.
a Isolated yields of product.