Paal–Knorr Pyrrole Synthesis Using Recyclable Amberlite IR 120 Acidic Resin: A Green Approach

Abstract

Amberlite IR 120 acidic resin, a polymer matrix, has been demonstrated as a catalyst for Paal-Knorr condensation of 2,5-hexadione with primary amines under solvent-free conditions. This is an efficient, mild, and green methodology for N-substituted pyrrole derivatives.

GRAPHICAL ABSTRACT

Keywords:

• Amberlite IR 120
• Paal–Knorr condensation
• pyrrole
• solvent free

ACKNOWLEDGMENT

The authors are very grateful to the University Grants Commission India (UGC) for financial assistance.

Notes

Note. All the compounds were characterized by ¹H NMR, ¹³C NMR, and mass spectra and verified by comparison with literature/authentic samples.