Cis-1,4-bis(triphenylphosphonium)-2-butene Peroxodisulfate as an Efficient Reagent for the Synthesis of Phenacyl Thiocyanates and Phenacyl Azides

Abstract

Styrenes efficiently undergo thiocyanation and azidation with cis-1,4-bis(triphenylphosphonium)-2-butene peroxodisulfate at 0 °C to furnish the corresponding thiocyanatoketones and azidoketones. This method is a direct, one-pot synthesis under mild condition using methanol as solvent.

GRAPHICAL ABSTRACT

Keywords:

• Cis-1,4-bis(triphenylphosphonium)-2-butene peroxodisulfate
• phenacyl azide
• phenacyl thiocyanate
• styrene

ACKNOWLEDGMENT

We thank Islamic Azad University, Shoushtar Branch, for financial support of this work.

Notes

^a According to GC analysis.

^a Products were identified by comparison of their physical and spectral data with those of authentic samples.

^a Products were identified by comparison of their physical and spectral data with those of authentic samples.