Iodination of Activated Aromatic Compounds Using Nanostructure Solid Acid Catalyst

Abstract

Nanoporous silica anchored with sulfonic acid groups effectively catalyzes the iodination of aromatic compounds. The reaction was performed in water using hydrogen peroxide as oxidant. The recyclability of catalyst in green media significantly contributes to the environmental friendliness of the procedure.

GRAPHICAL ABSTRACT

Keywords:

• Aromatic compounds
• green chemistry
• hydrogen peroxide
• iodination

ACKNOWLEDGMENT

We are grateful to the research councils of Mazandaran University for their financial support.

Notes

Note. Reaction conditions: 1,3,5-trimethoxybezene (1 mmol), iodine (0.5 mmol), and hydrogen peroxide (0.6 mmol) at (45 °C).

^a Substrate (1 mmol), I₂ (0.5 mmol), H₂O₂ (0.6 mmol), and MCM-41-SO₃H (5 mol%, 0.045 g).

^b Isolated yield.

^c 3 mol% of catalyst was used.

^d Yield in parentheses corresponds to diiodo product.

^e Molar ratio of reagents: substrate (1 mmol), I₂ (1 mmol), H₂O₂ (1.2 mmol), and MCM-41-SO₃H (7 mol%, 0.06 g).

^f Temperature of the process: 55 °C.