Abstract
A new helically chiral pentacyclic phosphine, containing one thiophene ring, was prepared in good yield and purity via a five-step sequence involving a Wittig reaction, a palladium-catalyzed Mizoroki–Heck coupling, and classical oxidative photocyclization reactions. The investigation using ultraviolet–visible spectroscopy shows that the helicene precursor of the target helical phosphine as well as its phosphine oxide have interesting behaviors.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
The authors are grateful to Direction Générale de la Recherche Scientifique of the Tunisian Ministry of Higher Education and Scientific Research for financial support.