Abstract
A simple and efficient protocol is developed for the preparation of bibrachial chiral heterodentate ligands bearing two amino acid or peptide side chains on different scaffolds.
GRAPHICAL ABSTRACT
![](/cms/asset/2a90d1ad-6e36-4067-985e-f645209e6999/lsyc_a_597534_o_uf0001.jpg)
ACKNOWLEDGMENTS
This study was performed with financial support by the Byelorussian Foundation for Basic Research (Project No. Kh08R-051), the Russian Foundation for Basic Research (Project No. 08-03-90 025), and partly by a grant from the president of the Russian Federation (Project No. MK-3588.2008.3).
Notes
a A mixture of intramolecular cyclization products was isolated.
a Oily substances.
b Spectra recorded in CDCl3.
c Spectra recorded in D2O.
a Spectra recorded in D2O.