Reaction of Diphenacylanilines with 2-Aminobenzophenone: An Abnormal Friedlander Reaction Yielding Indoles

Abstract

GRAPHICAL ABSTRACT

Keywords:

• Abnormal Friedlander reaction
• 2-aroyl-3-arylindole
• (±)-camphorsulfonic acid
• diphenacylaniline

ACKNOWLEDGMENTS

The authors thank the Department of Science and Technology, New Delhi, for funds under IRHPA program for the high-resolution NMR spectrometer and the University Grants Commission, New Delhi, for the financial support to one of the authors, N. P. N. Srinivasan of Thiagarajar College, Madurai, Tamil Nadu, India, and J. C. Menendez of Departamento de Quimica Organica y Farmaceutica, Universidad Complutense, Madrid, Spain, are acknowledged for the X-ray diffraction and mass analyses respectively.

Notes

^a Recrystallized from ethyl acetate.

^b No characteristic product.

^c Separated through column.

^d Reactants recovered.

^a After purification by recrystallization.