Abstract
2-Aminoimidazolidin-4-ones have been synthesized by using di-2-pyridyl thiocarbonate (DPT), taking the thioureas tethered to amides as the starting materials. Both the primary amides and secondary amides have been subjected to this cyclization method and in general this simple and convenient method was found to ensure good to excellent yields (81–99%).
GRAPHICAL ABSTRACT
Notes
a Compounds are known, and the spectral data are available in Refs. 10 and 11.
b Isolated yields.
c THF was used as solvent.
d CH3CN was used as solvent.
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