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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 45, 2015 - Issue 12
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Original Articles

Copper-Catalyzed Synthesis of Valuable Heterocyclic Compounds Using a Tandem Oxidation Process Approach

, &
Pages 1484-1491 | Received 12 Feb 2015, Published online: 05 May 2015
 

Abstract

The synthesis of quinoxalines via a tandem oxidation process using a copper acetate monohydrate/2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) oxidative system has been described. Using this approach, a series of quinoxaline derivatives were formed in good yields within short reaction times under microwave irradiation. The oxidative system was also extended to the selective synthesis of dihydropyrazines and pyrazines.

GRAPHICAL ABSTRACT

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