ABSTRACT
A simple and efficient one-pot protocol is accomplished to access tricyclic spiro dihydrofurans (4) by the reaction of β-enamino ketones (1) and dimedone (2) in ethanol followed by sequential addition of N-chlorosuccinimide at ambient temperature for the first time. The selectivity in desired product formation in good yields is the advantage of this protocol.
GRAPHICAL ABSTRACT
Acknowledgment
BCJ is thankful to UGC, New Delhi for SRF.
Supplementary data
Experimental procedures, characterization, and spectral data for all the synthesized compounds and X-ray diffraction crystallographic data for the compound 4a which has been deposited on CCDC with deposition number 1450194 can be available free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html or from the Cambridge Crystallographic Data Centre (CCDC), 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(0) 1223 336 033; email: www.ccdc.cam.ac.uk/data_request/cif)