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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 47, 2017 - Issue 17
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Original Articles

Synthesis and antimicrobial evaluation of some novel dithiolane, thiophene, coumarin, and 2-pyridone derivatives

Mahmoud R. MahmoudFaculty of Science, Department of Chemistry, Ain Shams University, Abbassia, Cairo, Egypt
,
Fatma S. M. Abu El-AzmFaculty of Science, Department of Chemistry, Ain Shams University, Abbassia, Cairo, EgyptCorrespondence[email protected]
,
Amira T. AliFaculty of Science, Department of Chemistry, Ain Shams University, Abbassia, Cairo, Egypt
&
Yasmeen M. AliFaculty of Science, Department of Chemistry, Ain Shams University, Abbassia, Cairo, Egypt
Pages 1591-1600 | Received 26 Feb 2017, Published online: 06 Jul 2017
 
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ABSTRACT

Novel 2-cyano-N-[1-(naphtha-2-yl)ethylidene] acetohydrazide 1 was utilized as key intermediate for the synthesis of some new dithiolane, thiophene, coumarin, 2-pyridone, and other related products containing a hydrazide moiety. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1H NMR and mass spectra). The antimicrobial activity of the synthesized compounds was evaluated.

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