Facile one-pot synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives by ultrasonic irradiation

ABSTRACT

Herein, we report an ultrasonic promoted facile and convenient “one-pot” procedure for the synthesis of new [1,2,4]triazolo[1,5-a]pyridine derivatives 3, 4 and 5, using Amberlite IRA-400, in short reaction times and high yields and its comparison with classical reaction conditions. The structures of new compounds were assigned with the help of analytical ¹H, ¹³C NMR, and mass spectral studies.

GRAPHICAL ABSTRACT

KEYWORDS:

• Amberlite IRA-400
• multicomponent reaction
• one-pot synthesis
• triazolopyridines
• ultrasound irradiation

Additional information

Funding

This work was supported by Regional Council of Franche-Comte [Grant Numbers 2016YC-04540, 04560].