ABSTRACT
In this article, direct N-alkylation of secondary amines with carboxylic acid is described. Readily available diversified carboxylic acid has been explored on variant secondary amines using encapsulated Nickel as catalyst and inexpensive sodium borohydride as the hydride source. High yields, mild reaction conditions, tolerance to sensitive functional group and facile operational procedure are the significance of the present methodology.
GRAPHICAL ABSTRACT
Acknowledgment
We acknowledge the management of Dr. Rafiq Zakaria College for women Aurangabad.