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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 16
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Original Articles

Synthesis, characterization and antibacterial activity of some new thiazole and thiazolidinone derivatives containing phenyl benzoate moiety

ORCID Icon, , &
Pages 2083-2092 | Received 12 Mar 2018, Published online: 09 Jul 2018
 

Abstract

4-Formylphenyl benzoate was utilized as a versatile precursor for the construction of new series of heterocyclic scaffolds that contain thiazole and thiazolidin-5-one rings. The antibacterial activity of these scaffolds against two types of bacteria was screened and most of them exhibited good activity. Among the synthesized thiazole derivatives, compounds 5, 6, and 8a showed antibacterial activity close to the standard chemotherapeutic (Ampicillin).

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