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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 18
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Research Paper

Synthesis and anti H5N1 activities of some novel fused heterocycles bearing pyrazolyl moiety

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Pages 2409-2419 | Received 01 May 2018, Published online: 29 Aug 2018
 

Abstract

Ring transformation of the acid hydrazide, derived from 2(3H)-furanone, into triazolopyridazine, triazolothiadiazole, and triazolothiadiazine derivatives, was investigated. The structures of all synthesized compound were demonstrated on the basis of their analytical and spectral data. The antiviral effect of the synthesized compounds against the highly pathogenic avian influenza (HPAI H5N1) was evaluated.

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