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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 20
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Articles

Zn(ANA)2Cl2 complex as efficient catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles in aqueous medium via one-pot multicomponent reaction: a green approach

, , &
Pages 2642-2651 | Received 17 Jun 2018, Accepted 25 Jul 2018, Published online: 14 Nov 2018
 

Abstract

The first example of recyclable Zn(ANA)2Cl2 catalyzed tandem one-pot three-component protocol reaction between aromatic aldehydes, malononitrile, and phenylmethylpyrazolone to furnish 4-substituted-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (4a–l) in a short reaction time (∼10 min) in aqueous media at room temperature is described.

Graphical Abstract

Acknowledgments

RK thanks the MHRD, New Delhi for a senior research fellowship.

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