Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 48, 2018 - Issue 23
Submit an article Journal homepage
374
Views
9
CrossRef citations to date
0
Altmetric
Articles

An efficient heterogeneous gold(I)-catalyzed hydration of haloalkynes leading to α-halomethyl ketones

Sifan HuKey Laboratory of Functional Small Organic Molecule, Ministry of Education and College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, China; View further author information
,
Dayi LiuKey Laboratory of Functional Small Organic Molecule, Ministry of Education and College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, China; View further author information
,
Chenyu YanAffiliated Middle School of Jiangxi Normal University, Nanchang, ChinaView further author information
&
Mingzhong CaiKey Laboratory of Functional Small Organic Molecule, Ministry of Education and College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, China; Correspondence[email protected]
View further author information
Pages 2983-2991 | Received 28 Jul 2018, Published online: 08 Nov 2018
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

A highly efficient heterogeneous gold(I)-catalyzed hydration of haloalkynes has been developed that proceeds smoothly under mild and neutral conditions and provides a general and practical route for the synthesis of a variety of α-halomethyl ketones with high atom-economy, excellent yield, and recyclability of the gold(I) catalyst. The presented method delivers an attractive alternative to classical α-halogenation of ketones.

Graphical Abstract

Additional information

Funding

We thank the National Natural Science Foundation of China (No. 21462021), the Natural Science Foundation of Jiangxi Province of China (No. 20161BAB203086), and Key Laboratory of Functional Small Organic Molecule, Ministry of Education (No. KLFS-KF-201704) for financial support.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.