Synthesis of 2-sulfenylindenones by visible-light-mediated addition of sulfur-centered radicals to 1,3-diarylpropynones

Abstract

A novel, visible-light-mediated method for the synthesis of 2-sulfenylindenones from easily available thiophenols (2.0 equiv.) and 1, 3-diarylpropynones (1.0 equiv.) in the presence of eosin Y (0.02 equiv.) under air atmosphere has been developed. The reaction proceeded smoothly, for a wide range of derivatives of thiophenols and 3-diarylpropynones, to give the expected products in moderate to good yields. Compared with traditional methods, this method is more convenient and avoids using stoichiometric amounts of I₂ and K₂S₂O₈.

Graphical Abstract

Keywords:

• Visible-light-mediate
• indenone
• eosin Y
• 1
• 3-diarylpropynone
• thiophenol

Additional information

Funding

We are grateful to the Fujian Province Young and Middle-aged Teacher Education Research Project (JAT160655), Innovation Training Program for College Students (201813470007), and the Fuzhou University Zhicheng College, for the support of this work.