Abstract
In this paper, an enantioselective synthesis of diplodialide-B has been described. To accomplish this target, a combination of regioselective ring opening of the chiral epoxide, Jacobsen hydrolytic kinetic resolution and Yamaguchi macrolactonization were used as the key steps.
Graphical Abstract
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Acknowledgments
The authors are thankful to CSIR-Indian Institute of Chemical Technology, Hyderabad and CSIR, New Delhi for constant encouragement in providing laboratory facilities and analytical data.