Abstract
An efficient and novel protocol for pyrazole synthesis has been developed by using fluoroboric acid as the acid catalyst. Simple and easily available 1,3-diketone and hydrazine derivatives are taken as the substrates for this purpose. The reaction entails mild reaction conditions and produces desired pyrazoles in good to excellent yields. Easy accessibility, easy handling, broad substrate scope, evading metal catalyst and economic viability make this protocol advantageous to most of the previously reported literature.
GRAPHICAL ABSTRACT
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Supporting information
General Information, Experimental and Analytical data, 1H and 13C NMR spectra and characterization data all are found in the “Supplementary Content” section of this article’s webpage.
Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.