![Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/110819/TOC-Subject-Sample-2021-Physical-Sciences.jpg"})
Abstract
Two reaction systems have been developed for the decarboxylation of indole-3-carboxylic acids. The decarboxylation can be achieved smoothly under K2CO3-catalyzed or acetonitrile-promoted basic conditions. It provided an efficient and simple method for the transformation of indole-3-carboxylic acids and the corresponding indoles were isolated with good to excellent yields. From the experimental facts, we put forward the possible reaction mechanism.
Graphical Abstract
Additional information
Funding
The work was supported by the Natural Science Foundation of Guizhou Province [Grant No. qiankehejichu [2018] number 1141], the Science and Technology Foundation Project of Liupanshui [Grant No. 52020-2018-04-10] and National Natural Science Foundation of China [No. 21763017].