Iodine mediated synthesis of diaryl diselenides using SeO₂ as a selenium source

Abstract

A simple, eco-friendly and convenient procedure has been developed for the synthesis of diphenyl diselinides from readily available aryl boronic acids by reaction with SeO₂ in the presence of iodine under simple conditions. The methodology is reported about 19 examples and applicable to a broad scope of aryl boronic acids containing electron-rich and electron-poor substituents. Apart from being milder and environmentally benign conditions, this synthetic protocol comprises a novel, reliable methodology to give good to high yields of the desired diaryl diselenides.

GRAPHICAL ABSTRACT

Keywords:

• Aryl boronic acids
• selenium dioxide
• iodine
• diaryl diselenides. 2-Me-THF

Additional information

Funding

We thank DICP for providing Analytical instruments data, this study was funded by the National Natural Science Foundation of China [Nos. 21721004].