Abstract
An efficient synthesis of 1,5-diaryl-4-benzothiazolyl-substituted 1,2,3-triazoles by organocatalytic 1,3-dipolar cycloaddition reactions, from easily available benzo[d]thiazole derivatives and substituted azidobenzenes, has been developed. The 1,8-diazabicyclo[5,4,0]undec-7-ene is used as organocatalyst, and the 2-(1,5-diaryl-1H-1,2,3-triazol-4-yl)benzo[d]thiazoles were obtained in good yields (60% − 82%) with regiospecificity. The structures of all synthesized compounds were confirmed by 1H NMR, 13C NMR and HRMS.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the author(s).