Synthetic approaches toward piperidine related structures: A review

Abstract

The current review covers explosive development of various synthetic approaches for piperidine scaffold and its analogues in the last few decades. The piperidine ring system is a key motif in many natural alkaloids and synthetic organic compounds. Further, piperidine moiety has gained significant consideration in drug discovery due to its wide range of therapeutic applications.

Graphical Abstract

Keywords:

• Alkaloid
• piperidine
• six membered nitrogen containing heterocycles
• synthetic approaches

Acknowledgments

We are thankful to Government College University, Faisalabad for providing facilities. We are thankful to Higher Education Commission (HEC) of Pakistan for funding Ayesha Bari for IRSIP Scholarship program.