Abstract
A mild and convenient route for the synthesis of isoxazole derivatives has been developed using ZSM-5 as a heterogeneous catalyst. The reaction was carried out under a solvent-free condition to afford the desired products in good yields. A variety of functional groups was tolerated under the reaction conditions employed. Moreover, the heterogeneous catalyst (ZSM-5) was recovered and reused several times without significant loss of its catalytic activity.
Graphical Abstract
![](/cms/asset/f471763a-dd72-43cd-9e82-7acf934f7d94/lsyc_a_1815786_uf0001_c.jpg)