A decade updates (2011–2020): Reduction of sulfoxides to sulfides

Abstract

Sulfides (compounds containing C–S–C bond) are an important class of organic compounds and are of great importance due to their many biological properties and their valuable application in various areas including industrial, pharmaceutical and agricultural chemistry. Given the importance of these compounds, research on the synthesis of sulfides is always an important challenge and topic in organic synthesis. Amongst different approaches, the straightforward deoxygenation of sulfoxides to sulfides has attracted profound attention. During the last decade, reducing systems for the reduction of sulfoxides to sulfides have been reported in the literature of many publications. The present review focuses on the methods reported for the straightforward deoxygenation of sulfoxides to sulfides over the last decade (2011–2020).

Graphical Abstract

Keywords:

• A decade updates (2011–2020)
• deoxygenation
• pharmaceutical chemistry
• sulfides
• sulfoxides

Additional information

Funding

This work was supported by NSFC [32060670].