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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 51, 2021 - Issue 24
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Articles

A facile and green synthetic protocol for 1,2,3-triazole linked thioethers/thioesters

Archana Vellingiria Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, IndiaView further author information
,
Jaabil Georgeb Department of Science and Humanities, DMI Engineering College, Kanyakumari, IndiaView further author information
,
Gnana kumar Georgepetera Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, IndiaView further author information
&
Ponnuswamy Alagusundarama Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-1564-2076View further author information
ORCID Icon
Pages 3748-3757 | Received 12 Jul 2021, Published online: 19 Oct 2021
 
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Abstract

Thiol-Michael addition of thiophenol/thiobenzoic acid to 1,2,3-triazole linked chalcone was investigated under greener solvent-free condition. A simple one-pot multicomponent protocol has been achieved under mild conditions at ambient temperature in excellent yield. The protocol is advantageous as it is atom economic, cost-effective, eco-friendly, avoiding multi-step procedure and purification techniques.

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Funding

We are grateful for support from Department of Science and Technology, New Delhi, India for funds under IRPHA program for the purchase of NMR spectrometer.

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