Synthesis of heterocycles from propargylamines

Abstract

Research on the synthesis of heterocyclic compounds is always a hot research topic among synthetic chemists, because heterocycles are very important scaffolds in the structure of numerous drugs, natural products and biologically active molecules. Propargylamines are a versatile class of amine compounds which find many applications in different fields of chemistry such as synthetic chemistry. In recent times, the utilization of propargylamines as reagent for the synthesis of heterocyclic compounds have received profound attention in organic synthesis. This review will provide comprehensive knowledge on the utilization of propargylamines as versatile and efficient reagents in the synthesis of heterocyclic compounds.

Graphical Abstract

Keywords:

• Propargylamines
• versatile reagent
• synthetic approaches
• heterocycles
• organic synthesis