Abstract
2-Benzylpyridines scaffolds have been found in various drugs, bioactive natural products, and medicinally important compounds. This manuscript comprises the synthesis of various fluorinated analogs of 2-benzylpyridine compounds by using a Negishi coupling reaction as a key reaction.
Graphical Abstract
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Acknowledgments
The authors acknowledge ICT-IOC, Bhubaneswar for providing necessary support. Rambabu Dandela thanks DST-SERB for the Ramanujan fellowship (SB/S2/RJN-075/2016), Core Research grant (CRG/2018/000782), and ICT-IOC start-up grant. BT is thankful for the financial support from the Indian Institute of Science Education and Research Berhampur in the form of an initiation grant (IG/201818/B0034). We thank Dr. Gurupada Hazra for helping us to collect spectral and analytical data.