Abstract
Magnetic nanofiber cellulose (NFC) was selected as a biopolymer surface for the reaction with ferric metformin and a novel nanocatalyst was prepared. This green heterogeneous organometallic catalyst was analyzed by physiochemical techniques. The new metformin drug complex supported on magnetic NFC was used as a powerful and efficient catalyst for the synthesis of functionalized 4H-pyrans derivatives. The antimicrobial activity of the products showed excellent activity against all the bacterial and fungal strains (especially compounds 7q and 6r).
Graphical Abstract
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Acknowledgments
The authors are thankful to Iran National Science Foundation (INSF) and Sharif University of Technology Laboratory Services Center. Thanks to Dr. Zahra Daneshfar for helping us with this project.
Disclosure statement
The authors have no conflict of interest to declare.