FeCl₃ as an efficient catalyst for the synthesis of styrylquinoxalin-2(1H)-ones

Abstract

The synthesis of (E)-3-substituted styrylquinoxalin-2(1H)-ones was achieved by the reaction of 3-methylquinoxalinone and aromatic aldehydes using FeCl₃ as a catalyst in toluene under microwave irradiation. The protocol is endowed with milder reaction conditions, high yields of product, and easy workup procedures.

Graphical Abstract

Keywords:

• FeCl₃
• metal catalyst
• microwave
• styrylquinoxalin-2(1H)-ones

Acknowledgments

Authors are highly thankful to Department of Chemistry, University of Jammu, Jammu for providing all necessary facilities and DST PURSE for NMR facility. RPS is thankful to University Grant Commission (UGC) for the award of junior research fellowship.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work was supported by University Grants Commission.