Abstract
Cycl[3.2.2]azine molecules are widely found in both synthetic chemistry and natural products. They have shown promising applications in a variety of research fields. The development of facile and stereoselective methods for the synthesis of cycl[3.2.2]azine derivatives has attracted great interests in recent years. Representative acheivements in the construction of cycl[3.2.2]azine molecules in both enantioselective and non-asymmetric fahsion are systematically reviewed.
Graphical Abstract
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Acknowledgments
We acknowledge funding supports from Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules, Department of Education, Guizhou Province [Qianjiaohe KY number (2020)004]; Program of Introducing Talents of Discipline to Universities of China (111 Program, D20023) at Guizhou University.