FeCl₃ Immobilized in Al-MCM 41: An Efficient Catalyst System for the Biginelli Reaction

Abstract

FeCl₃ immobilized on Al-MCM-41 was found to be an efficient catalytic system for the one-pot synthesis of 3,4-dihyropyrimidinone derivatives. This is a facile and high-yielding reaction for synthesis of the 3,4-dihyropyrimidinone. The catalyst exhibited remarkable reactivity and is reusable.

Keywords:

• Biginell
• 3,4-dihyropyrimidinone
• Fe(III)/Al-MCM-41
• three-component condensation

ACKNOWLEDGMENT

We are grateful to the Alzahra University Research Council for partial support of this work.

Notes

^a Products were characterized by comparison of their spectroscopic data (GC mass, IR, mps) and ¹H NMR with those reported in the literature.

^b Isolated yield.

^a Isolated yield.