Abstract
Under microwave irradiation, the one-pot multicomponent condensation reaction of three molar aromatic aldehydes with two molar cyclic ketones having free α,α′-methylene positions such as cyclopentanone or cyclohexanone in the presence of ammonium acetate and acetic acid afforded dicyclocalkenopyridines with two α-arylidene groups in good yields. In similar reaction conditions, 1-tetralone, which has only one α-methylene position, results in 10-aryl-2,3:5,6-dibenzoacridines.
ACKNOWLEDGMENTS
This work was financially supported by the National Natural Science Foundation of China (Grant No. 20672091), China. We are grateful to Ms. Min Shao for assistance with measuring the x-ray single-crystal structures.