Facile and Mild Process for Chemical Fixation of CO₂ to 4-Methylene-1,3-oxazolidin-2-ones Under Solvent-Free Conditions

Abstract

4-Methylene-1,3-oxazolidin-2-ones were prepared via the cycloadditon reaction of propargylic alcohols with primary amines and CO₂ under atmospheric pressure at 60 °C in the absence of any additional solvent. This methodology affords an ecofriendly, mild, and easy approach to chemical fixation of CO₂.

Keywords:

• Carbon dioxide
• chemical fixation
• oxazolidinone
• propargylic alcohol
• solvent-free

Notes

^a Condition: 2-methylbut-3-yn-2-ol (2 mmol), n-butylamine (2–6 mmol), catalyst (0.1 mmol).

^b Isolated yields based on 2-methylbut-3-yn-2-ol.

^c 2-Methylbut-3-yn-2-ol remained unchanged.

^a Reagents and conditions: alcohol 1 (2 mmol), amine 2 (4 mmol), CuCl (0.1 mmol), 60 °C, 24 h.

^b Isolated yield based on alcohol.

^c No desired product detected.

^d Alcohol remained unchanged.