Abstract
Silica chloride, a heterogeneous catalyst, has been found to be an efficient catalyst for the protection of aldehydes as acylals under solvent-free conditions, and deprotection of acylals to aldehydes in methanol as a solvent occurred. The reaction takes a shorter time and ensures good to excellent yield of the products.
Notes
a Isolated yield.
a All the acylals were characterized by comparison of the melting points with authentic samples [Refs. 27, 29] and by the IR spectral analysis.
b Deprotection was followed by GC-MS analysis.
c Isolated yields.
d ND, not detected.